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Ligand

NameThioperamide
Molecular formulaC15H24N4S
IUPAC nameN-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
Molecular weight292.445
Hydrogen bond acceptor2
Hydrogen bond donor2
XlogP2.4
Synonyms106243-16-7
Thioperamide maleate
MR 12842
UNII-II4319BWUI
1-Piperidinecarbothioamide, N-cyclohexyl-4-(1H-imidazol-4-yl)-
[ Show all ]
Inchi KeyQKDDJDBFONZGBW-UHFFFAOYSA-N
Inchi IDInChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)
PubChem CID3035905
ChEMBLCHEMBL260374
IUPHAR1267
BindingDB22914
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 32
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
2802545-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
2802585-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
2802565-hydroxytryptamine receptor 1DP28565Htr1dRattus norvegicus (Rat)374
5565655-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2802495-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
2802625-hydroxytryptamine receptor 4O70528HTR4Cavia porcellus (Guinea pig)388
280243Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
280245Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
280250Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
280260Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
461637Beta-2 adrenergic receptorP10608Adrb2Rattus norvegicus (Rat)418
280261Cholecystokinin receptor type AP30551CckarRattus norvegicus (Rat)444
280252D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
556564D(3) dopamine receptorP19020Drd3Rattus norvegicus (Rat)446
280240Delta-type opioid receptorP33533Oprd1Rattus norvegicus (Rat)372
280242Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
280247Histamine H1 receptorP31389HRH1Cavia porcellus (Guinea pig)488
280244Histamine H2 receptorP47747HRH2Cavia porcellus (Guinea pig)359
280263Histamine H2 receptorP25021HRH2Homo sapiens (Human)359
280235Histamine H3 receptorQ9Y5N1HRH3Homo sapiens (Human)445

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