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Ligand

NameFluspirilene
Molecular formulaC29H31F2N3O
IUPAC name8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight475.584
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP5.6
SynonymsRedeptin
Imap
1841-19-6
Fluspirileno
Fluspirilenum
[ Show all ]
Inchi KeyQOYHHIBFXOOADH-UHFFFAOYSA-N
Inchi IDInChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35)
PubChem CID3396
ChEMBLCHEMBL46516
IUPHAR85
BindingDB26948
DrugBankDB04842

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 39
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
2834795-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
2834845-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
2834705-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
2834835-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
2834665-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
2834895-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
2834675-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5565745-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2834925-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
2834855-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
283493Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
283482Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
283469Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
283487Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
283494Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
283476Beta-1 adrenergic receptorP08588ADRB1Homo sapiens (Human)477
283474Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413
283486Cysteinyl leukotriene receptor 1Q2NNR5CYSLTR1Cavia porcellus (Guinea pig)340
283464D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
283478D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446

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