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Ligand

Nameamoxapine
Molecular formulaC17H16ClN3O
IUPAC name8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine
Molecular weight313.785
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP2.6
SynonymsNCGC00015004-16
NSC-759559
Prestwick1_000102
SAM002564189
Spectrum2_001245
[ Show all ]
Inchi KeyQWGDMFLQWFTERH-UHFFFAOYSA-N
Inchi IDInChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2
PubChem CID2170
ChEMBLCHEMBL1113
IUPHAR201
BindingDB22870
DrugBankDB00543

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 35
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
2884055-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
2884335-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
2884175-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5547095-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2884235-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
2884085-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
2884195-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
2884185-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
2884325-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
2884285-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
2884305-hydroxytryptamine receptor 7P50407HTR7Cavia porcellus (Guinea pig)446
5547085-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
288435Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
453079Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
288409Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
288421Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
288427Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
288411Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
288406Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
288404D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446

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