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Ligand

NameCP-293019
Molecular formulaC19H22F2N4O
IUPAC name(7R,9aS)-7-[(4-fluorophenoxy)methyl]-2-(5-fluoropyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine
Molecular weight360.409
Hydrogen bond acceptor7
Hydrogen bond donor0
XlogP3.1
Synonyms(7R,9aalpha)-2-(5-Fluoro-2-pyrimidinyl)-7alpha-(4-fluorophenoxymethyl)octahydro-6H-pyrido[1,2-a]pyrazine
(7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine
(7R,9aS)-7-[(4-fluorophenoxy)methyl]-2-(5-fluoropyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine
7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine (CP-293019)
BDBM50069041
[ Show all ]
Inchi KeyQXWNESOGWFJDFR-PBHICJAKSA-N
Inchi IDInChI=1S/C19H22F2N4O/c20-15-2-5-18(6-3-15)26-13-14-1-4-17-12-25(8-7-24(17)11-14)19-22-9-16(21)10-23-19/h2-3,5-6,9-10,14,17H,1,4,7-8,11-13H2/t14-,17+/m1/s1
PubChem CID9820261
ChEMBLCHEMBL66227
IUPHAR977
BindingDB50069041
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
2895425-hydroxytryptamine receptor 1AQ64264Htr1aMus musculus (Mouse)421
2895385-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
289539D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
289541D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
289540D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467
554711D(4) dopamine receptorP30729Drd4Rattus norvegicus (Rat)387

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