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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL851533
Molecular formula	C26H26F3N5O6S
IUPAC name	3-[3-methyl-4-[2-[[4-oxo-2-[3-(trifluoromethoxy)phenyl]-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]imidazolidine-2,4-dione
Molecular weight	593.578
Hydrogen bond acceptor	11
Hydrogen bond donor	2
XlogP	2.8
Synonyms	US9428505, Comparative: Example 1 CHEMBL3959465 BDBM64569
Inchi Key	REOKUYXIRRUCMN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26F3N5O6S/c1-16-13-19(34-21(35)15-30-24(34)37)6-5-17(16)7-12-41(38,39)33-10-8-25(9-11-33)23(36)31-22(32-25)18-3-2-4-20(14-18)40-26(27,28)29/h2-6,13-14H,7-12,15H2,1H3,(H,30,37)(H,31,32,36)
PubChem CID	66818600
ChEMBL	CHEMBL3959465
IUPHAR	N/A
BindingDB	64569
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
535227	Parathyroid hormone/parathyroid hormone-related peptide receptor	P25961	Pth1r	Rattus norvegicus (Rat)	591

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