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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-162,313
Molecular formula	C30H38N4O4S2
IUPAC name	butyl N-[3-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate
Molecular weight	582.778
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	7.6
Synonyms	BDBM50049189 CHEMBL288174 NCGC00015596-01 SMR001230801 3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-ylmethyl)-phenyl]-5-isobutyl-thiophene-2-sulfonic acid butyloxycarbonylamide(L-162313) 5,7-Dimethyl-2-ethyl-3-[[4-[2-(n-butyloxycarbonylsulfonamido)-5-isobutyl-3-thienyl]phenyl]methyl]imidazo-[4,5-b]-pyridine butyl N-[3-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate FT-0732122 Lopac-L-1415 NCGC00015596-04 Tox21_500697 AC1O7G4F CCG-204782 L 1415 MFCD00915204 NCGC00261382-01 (5,7-dimethyl-2-ethyl-3-[[4-[2(n-butyloxycarbonylsulfonamido)-5-isobutyl-3-thienyl]phenyl]methyl]imidazo[4,5,6]pyridine butyl (3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)-5-isobutylthiophen-2-yl)sulfonylcarbamate D0A4NO L-162,313, >=95%, solid NCGC00015596-02 SR-01000076212 5,7-Dimethyl-2-ethyl-3-[[4-[2??(n-butyloxycarbonylsulfonamido)-5-isobutyl-3-thienyl]phenyl]methyl]imidazo??[4,5-b]??pyridine butyl N-[3-[4-[(2-ethyl-5,7-dimethylimidazo[5,4-b]pyridin-3-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate GTPL3936 Lopac0_000697 NCGC00094051-01 Z3214 AKOS030627241 L 162313 MLS002153426 SCHEMBL9132197 151488-11-8 butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)-5-isobutylthiophen-2-ylsulfonylcarbamate EU-0100697 L-162313 NCGC00015596-03 SR-01000076212-1 5,7-Dimethyl-2-ethyl-3-[[4-[2(N-butyloxycarbonylsulfonamido)-5-isobutyl-3-thienyl]phenyl]methyl]Imidazo[4,5,6]pyridine C30H38N4O4S2 HMS3262K15 LP00697 NCGC00094051-02 ZINC3918293 [ Show all ]
Inchi Key	RINPELQWLUGERM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H38N4O4S2/c1-7-9-14-38-30(35)33-40(36,37)29-25(17-24(39-29)15-19(3)4)23-12-10-22(11-13-23)18-34-26(8-2)32-27-20(5)16-21(6)31-28(27)34/h10-13,16-17,19H,7-9,14-15,18H2,1-6H3,(H,33,35)
PubChem CID	6603900
ChEMBL	CHEMBL288174
IUPHAR	3936
BindingDB	50049189
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
453468	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
296995	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
297000	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
297001	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764
296997	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
297002	Type-1 angiotensin II receptor	P30555	AGTR1	Sus scrofa (Pig)	359
296998	Type-1A angiotensin II receptor	P25095	Agtr1	Rattus norvegicus (Rat)	359
296996	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363
296999	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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