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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL274022
Molecular formula	C19H23N5O4
IUPAC name	2-(hydroxymethyl)-5-[6-(1-phenylpropan-2-ylamino)purin-9-yl]oxolane-3,4-diol
Molecular weight	385.424
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	2.0
Synonyms	BDBM50006730 L-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol SMR000326849 ()-N6-(2-Phenylisopropyl)adenosine 2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol CTK8H4974 R-N6-(2-phenylisopropyl) adenosine (R-PIa) 2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol AC1L1JFU HMS3371L16 S-PIA 2-(hydroxymethyl)-5-[6-(1-phenylpropan-2-ylamino)purin-9-yl]oxolane-3,4-diol L000522 VC30589 (-)-N6-(2-PHENYLISOPROPYL)-ADENOSINE D-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol R-PIA (S)-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol AC1Q4Y36 HMS3373F22 SCHEMBL14829806 2-(hydroxymethyl)-5-{6-[(1-phenylpropan-2-yl)amino]-9H-purin-9-yl}oxolane-3,4-diol ChEMBL_20163 MLS000859990 (R)-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol 9-pentofuranosyl-n-(1-phenylpropan-2-yl)-9h-purin-6-amine HMS2232M21 REGID_for_CID_5022 [ Show all ]
Inchi Key	RIRGCFBBHQEQQH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23N5O4/c1-11(7-12-5-3-2-4-6-12)23-17-14-18(21-9-20-17)24(10-22-14)19-16(27)15(26)13(8-25)28-19/h2-6,9-11,13,15-16,19,25-27H,7-8H2,1H3,(H,20,21,23)
PubChem CID	5022
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50006730
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
297124	Adenosine receptor A1	P49892	ADORA1	Gallus gallus (Chicken)	324
297125	Adenosine receptor A1	P47745	ADORA1	Cavia porcellus (Guinea pig)	326
297126	Adenosine receptor A1	P34970	ADORA1	Oryctolagus cuniculus (Rabbit)	328
297127	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
297129	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
297131	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
297132	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
297130	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
297122	Adenosine receptor A3	P35342	ADORA3	Ovis aries (Sheep)	317
297123	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318
297128	Adenosine receptor A3	O02667	ADORA3	Oryctolagus cuniculus (Rabbit)	319
297121	P2Y purinoceptor 2	P58825	P2RY2	Cricetulus griseus (Chinese hamster)	166

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