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Ligand

Namemethiothepin
Molecular formulaC20H24N2S2
IUPAC name1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine
Molecular weight356.546
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP4.2
SynonymsMetitepine
Methiothepine
Metitepinum
Metitepina
Metitepine [INN]
[ Show all ]
Inchi KeyRLJFTICUTYVZDG-UHFFFAOYSA-N
Inchi IDInChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3
PubChem CID4106
ChEMBLCHEMBL93240
IUPHAR89
BindingDB78940
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 35
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
2990245-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
2990305-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
2990205-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
2990235-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
2990465-hydroxytryptamine receptor 1BO08892HTR1BCavia porcellus (Guinea pig)389
2990155-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
2990445-hydroxytryptamine receptor 1DP79400HTR1DSus scrofa (Pig)291
2990475-hydroxytryptamine receptor 1DP28565Htr1dRattus norvegicus (Rat)374
2990275-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
2990345-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
2990455-hydroxytryptamine receptor 1FP30940Htr1fRattus norvegicus (Rat)366
2990225-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
2990255-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2990195-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
2990355-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
2990375-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
2990265-hydroxytryptamine receptor 5AP35364Htr5aRattus norvegicus (Rat)357
2990385-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
2990415-hydroxytryptamine receptor 5AP30966Htr5aMus musculus (Mouse)357
2990285-hydroxytryptamine receptor 5BP35365Htr5bRattus norvegicus (Rat)370

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