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Ligand

Namemirtazapine
Molecular formulaC17H19N3
IUPAC name5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene
Molecular weight265.36
Hydrogen bond acceptor3
Hydrogen bond donor0
XlogP3.3
Synonyms85650-52-8
Remeron
61337-67-5
Mepirzepine
Remergil
[ Show all ]
Inchi KeyRONZAEMNMFQXRA-UHFFFAOYSA-N
Inchi IDInChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
PubChem CID4205
ChEMBLCHEMBL654
IUPHAR7241
BindingDB50115644
DrugBankDB00370

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 32
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
3013305-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
3013555-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
3013345-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
3013465-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
3013485-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
3013415-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
3013425-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
3013495-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
301331Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
301337Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
301325Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
301327Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
301332Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
301324Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
301333Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
301340Beta-1 adrenergic receptorP08588ADRB1Homo sapiens (Human)477
301352Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413
301336D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
301345D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
301353D(1B) dopamine receptorP21918DRD5Homo sapiens (Human)477

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