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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL97200
Molecular formula	C24H27NO5
IUPAC name	(1S,2S,3S)-2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-methylpropyl)cyclopropane-1-carboxylic acid
Molecular weight	409.482
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	1.5
Synonyms	BDBM50072170 (1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-isobutyl-cyclopropanecarboxylic acid
Inchi Key	RQZMFVKQWUAIHP-CHYAVIAWSA-N
Inchi ID	InChI=1S/C24H27NO5/c1-13(2)11-16-20(22(26)27)21(16)24(25,23(28)29)12-17-14-7-3-5-9-18(14)30-19-10-6-4-8-15(17)19/h3-10,13,16-17,20-21H,11-12,25H2,1-2H3,(H,26,27)(H,28,29)/t16-,20+,21+,24?/m1/s1
PubChem CID	44329033
ChEMBL	CHEMBL97200
IUPHAR	N/A
BindingDB	50072170
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
303019	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
303020	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
303021	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
303023	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
303017	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
303022	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
303018	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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