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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Opc-4392
Molecular formula	C24H29N3O2
IUPAC name	7-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propoxy]-1H-quinolin-2-one
Molecular weight	391.515
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.0
Synonyms	7-(3-(4-(2,3-Dimethylphenyl)piperazinyl)propoxy)-2(1H)-quinolone CAS_163839 111073-34-8 D09ULA SCHEMBL2424904 2(1H)-Quinolinone,7-[3-[4-(2,3-dimethylphenyl)-1-piperazinyl]propoxy]- ACMC-20dcav NSC_163839 7-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propoxy]-1H-quinolin-2-one CHEMBL55171 PDSP1_000687 2(1H)-Quinolinone, 7-(3-(4-(2,3-dimethylphenyl)-1-piperazinyl)propoxy)- AC1L4TPA GTPL268 ZINC5116306 BDBM82065 Opc 4392 7-{3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propoxy}quinolin-2(1h)-one CTK4A7166 PDSP2_000677 2(1H)-Quinolinone, 7-[3-[4-(2,3-dimethylphenyl)-1-piperazinyl]propoxy]- AC1Q6O88 L001306 [ Show all ]
Inchi Key	RRLWEQBPSAFVAS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28)
PubChem CID	163839
ChEMBL	N/A
IUPHAR	268
BindingDB	82065
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
303329	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
554767	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
303328	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
303327	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
556681	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
556682	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
303331	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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