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Ligand

NameWAY-100635
Molecular formulaC25H34N4O2
IUPAC nameN-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexanecarboxamide
Molecular weight422.573
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP4.2
SynonymsCCG-205303
D08WYI
L000012
N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide
PDSP2_001699
[ Show all ]
Inchi KeySBPRIAGPYFYCRT-UHFFFAOYSA-N
Inchi IDInChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3
PubChem CID5684
ChEMBLCHEMBL31354
IUPHAR80, 3251
BindingDB86708
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 49
Page:  / 3 

GLASS IDNameUniProtGeneSpeciesLength
3102825-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
3102885-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
3102985-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
3102835-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
3103065-hydroxytryptamine receptor 1DQ61224Htr1dMus musculus (Mouse)374
3102995-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
3103225-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5567115-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
3103005-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
3102955-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
3103025-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
3102895-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
3102855-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
3102915-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
310305Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
310313Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
310303Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
310307Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
310316Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
310292Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450

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