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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ASN 04450772
Molecular formula	C26H25N5O6S
IUPAC name	4-amino-5-N-(furan-2-ylmethyl)-5-N-[1-(4-hydroxyphenyl)-2-[(4-methoxyphenyl)methylamino]-2-oxoethyl]-1,2-thiazole-3,5-dicarboxamide
Molecular weight	535.575
Hydrogen bond acceptor	9
Hydrogen bond donor	4
XlogP	2.6
Synonyms	AKOS000704805 HMS2894K03 TVONKIFIPYRNRD-UHFFFAOYSA-N 4-Amino-isothiazole-3,5-dicarboxylic acid 3-amide 5-{furan-2-ylmethyl-[(4-hydroxy-phenyl)-(4-methoxy-benzylcarbamoyl)-methyl]-amide} ASN04450772 N-Furfuryl-N-[alpha-(4-methoxybenzylcarbamoyl)-4-hydroxybenzyl]-4-amino-3-carbamoylisothiazole-5-carboxamide D07ZGV SCHEMBL2723465 MCULE-6018247339 4-amino-N'-(furan-2-ylmethyl)-N'-[1-(4-hydroxyphenyl)-2-[(4-methoxyphenyl)methylamino]-2-oxoethyl]-1,2-thiazole-3,5-dicarboxamide Oprea1_463091 AC1ML3KQ GTPL5519 SMR000600145 4-amino-5-N-(furan-2-ylmethyl)-5-N-[1-(4-hydroxyphenyl)-2-[(4-methoxyphenyl)methylamino]-2-oxoethyl]-1,2-thiazole-3,5-dicarboxamide ASN-04450772 MLS001219009 4-amino-N5-(2-furanylmethyl)-N5-[1-(4-hydroxyphenyl)-2-[[(4-methoxyphenyl)methyl]amino]-2-oxoethyl]-3,5-isothiazole dicarboxamide CHEMBL1466483 Oprea1_799954 [ Show all ]
Inchi Key	TVONKIFIPYRNRD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H25N5O6S/c1-36-18-10-4-15(5-11-18)13-29-25(34)22(16-6-8-17(32)9-7-16)31(14-19-3-2-12-37-19)26(35)23-20(27)21(24(28)33)30-38-23/h2-12,22,32H,13-14,27H2,1H3,(H2,28,33)(H,29,34)
PubChem CID	3188786
ChEMBL	CHEMBL1466483
IUPHAR	5519
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
328514	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
554903	Uracil nucleotide/cysteinyl leukotriene receptor	Q13304	GPR17	Homo sapiens (Human)	367

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