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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL544099
Molecular formula	C18H27NO2
IUPAC name	(1R,3S)-3-cyclohexyl-6-methyl-1-(methylaminomethyl)-3,4-dihydro-1H-isochromen-5-ol
Molecular weight	289.419
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.7
Synonyms	SCHEMBL9802511 3-Cyclohexyl-6-methyl-1-methylaminomethyl-isochroman-5-ol; hydrobromide CHEMBL1192799 (1R)-1alpha-(Methylaminomethyl)-3,4-dihydro-3alpha-cyclohexyl-6-methyl-1H-2-benzopyran-5-ol BDBM50008831
Inchi Key	TWJRNAUVADBAOE-IRXDYDNUSA-N
Inchi ID	InChI=1S/C18H27NO2/c1-12-8-9-14-15(18(12)20)10-16(21-17(14)11-19-2)13-6-4-3-5-7-13/h8-9,13,16-17,19-20H,3-7,10-11H2,1-2H3/t16-,17-/m0/s1
PubChem CID	15711855
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50008831
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
567590	D(1) dopamine receptor	P35406		Carassius auratus (Goldfish)	363
329089	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
329090	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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