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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	RS-67506
Molecular formula	C18H28ClN3O4S
IUPAC name	N-[2-[4-[3-(4-amino-5-chloro-2-methoxyphenyl)-3-oxopropyl]piperidin-1-yl]ethyl]methanesulfonamide
Molecular weight	417.949
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	1.7
Synonyms	RS 67506 1-(4-Amino-5-chloro-2-methoxyphenyl)-3-[1-(2-methylsulfonylaminoethyl)-4-piperidinyl]-1-propanone BPBio1_000485 L000652 NCGC00024921-01 SCHEMBL548884 CHEBI:92869 PDSP1_001645 ZINC600432 BDBM84951 D07OSA 1-[4-Amino-5-chloro-2-methoxyphenyl]-3-{1-[2-(methylsulfonyl) aminoethyl]-piperidin-4-yl}propan-1-one BRD-K50018155-003-01-3 N-(2-{4-[3-(4-amino-5-chloro-2-methoxyphenyl)-3-oxopropyl]piperidin-1-yl}ethyl)methanesulfonamide NCGC00024921-02 Tocris-0990 AC1L324X PDSP2_001629 Biomol-NT_000147 GTPL3230 RS67506 CAS_133075 N-[2-[4-[3-(4-amino-5-chloro-2-methoxyphenyl)-3-oxopropyl]piperidin-1-yl]ethyl]methanesulfonamide NSC_133075 UATDVRSFFGFTAI-UHFFFAOYSA-N AJ-23660 CHEMBL83899 [ Show all ]
Inchi Key	UATDVRSFFGFTAI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H28ClN3O4S/c1-26-18-12-16(20)15(19)11-14(18)17(23)4-3-13-5-8-22(9-6-13)10-7-21-27(2,24)25/h11-13,21H,3-10,20H2,1-2H3
PubChem CID	133076
ChEMBL	CHEMBL83899
IUPHAR	3230
BindingDB	84951
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
332172	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
556829	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
332167	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
332166	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
332170	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
556828	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
332169	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
332177	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
332176	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
332171	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
332173	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
462097	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
462096	D(1A) dopamine receptor	O77680	DRD1	Macaca mulatta (Rhesus macaque)	446
332168	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
332174	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466

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