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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL346389
Molecular formula	C19H20ClN3O2
IUPAC name	7-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-4H-1,4-benzoxazin-3-one
Molecular weight	357.838
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.9
Synonyms	CI-1030 7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one ZINC53057273 L001598 7-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-4H-1,4-benzoxazin-3-one SCHEMBL6910062 BDBM50083342 [ Show all ]
Inchi Key	UFFHNEZNXKJHFB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H20ClN3O2/c20-15-2-4-16(5-3-15)23-9-7-22(8-10-23)12-14-1-6-17-18(11-14)25-13-19(24)21-17/h1-6,11H,7-10,12-13H2,(H,21,24)
PubChem CID	9885114
ChEMBL	CHEMBL346389
IUPHAR	N/A
BindingDB	50083342
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
335435	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
335436	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
335440	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
335441	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
335442	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
335437	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
335439	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
335438	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
335443	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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