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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	MLS000756415
Molecular formula	C20H25N3O2
IUPAC name	N-(1-hydroxybutan-2-yl)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Molecular weight	339.439
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.3
Synonyms	HMS3369A11 NSC-186067 CAS_8226 Methergin (Salt/Mix) SCHEMBL16092804 9,10-Didehydro-N-(.alpha.-(hydroxymethyl)propyl)-6-methyl-ergoline-8-.beta.-carboxamide CHEMBL1597692 Ergoline-8.beta.-carboxamide, 9,10-didehydro-N-[(S)-1-(hydroxymethyl)propyl]-6-methyl- N-[.alpha.-(Hydroxymethyl)propyl]-D-lysergamide BDBM86237 L000928 NSC186067 4,6,6a,7,8,9-Hexahydro-9-[1-(hydroxymethyl)propylcarbamoyl]-7-methylindolo[4,3-fg]quinoline CHEBI:91798 Ergoline-8-carboxamide, 9,10-didehydro-N-[(1S)-1-(hydroxymethyl)propyl]-6-methyl-, (8.beta.)- Methergine (Salt/Mix) SMR000528720 9,10-Didehydro-N-[(S)-1-(hydroxymethyl)propyl]-6-methylergoline-8.beta.-carboxamide HMS2231B08 N-[1-(Hydroxymethyl)propyl]-6-methyl-9,10-didehydroergoline-8-carboxamide, [8.beta.(S)]- # BRD-A63667919-103-01-9 MCULE-8879242487 NSC_8226 Ergoline-8-carboxamide, 9,10-didehydro-N-[1-(hydroxymethyl)propyl]-6-methyl-, [8.beta.(S)]- UNBRKDKAWYKMIV-UHFFFAOYSA-N AC1L1HI4 [ Show all ]
Inchi Key	UNBRKDKAWYKMIV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H25N3O2/c1-3-14(11-24)22-20(25)13-7-16-15-5-4-6-17-19(15)12(9-21-17)8-18(16)23(2)10-13/h4-7,9,13-14,18,21,24H,3,8,10-11H2,1-2H3,(H,22,25)
PubChem CID	4140
ChEMBL	CHEMBL1597692
IUPHAR	N/A
BindingDB	86237
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
340747	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
340746	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
340748	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
340750	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
340749	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
340745	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
340744	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
505060	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
340751	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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