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Ligand

NameCHEMBL35226
Molecular formulaC21H29N3O
IUPAC name5-[(1-propylpiperidin-4-yl)methoxy]-1,2,3,4-tetrahydrobenzo[h][1,6]naphthyridine
Molecular weight339.483
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP4.5
SynonymsBDBM50122716
L021962
5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahydro-benzo[h][1,6]naphthyridine
6-(1-Propylpiperidine-4-ylmethoxy)-7,8,9,10-tetrahydro-10-azabenzo[c]quinoline
Inchi KeyUTMXFLLOSBJGIE-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3
PubChem CID9881053
ChEMBLCHEMBL35226
IUPHARN/A
BindingDB50122716
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 16
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
3452155-hydroxytryptamine receptor 1AQ64264Htr1aMus musculus (Mouse)421
3452185-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
3452085-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
3452035-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
3452025-hydroxytryptamine receptor 4O70528HTR4Cavia porcellus (Guinea pig)388
3452055-hydroxytryptamine receptor 4P97288Htr4Mus musculus (Mouse)388
3452175-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
3452125-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
345213Beta-1 adrenergic receptorP08588ADRB1Homo sapiens (Human)477
345216Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413
345204D(1A) dopamine receptorQ61616Drd1Mus musculus (Mouse)446
345209D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
345210Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
345207Histamine H2 receptorP25102Hrh2Rattus norvegicus (Rat)358
345214Vasopressin V1b receptorP48974Avpr1bRattus norvegicus (Rat)425
345211Vasopressin V2 receptorP32307AVPR2Sus scrofa (Pig)370

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