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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Exp7711
Molecular formula	C22H23ClN2O3
IUPAC name	2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzoic acid
Molecular weight	398.887
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.6
Synonyms	4''-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid AKOS030533254 4'-Imi CHEMBL274447 SCHEMBL89 2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-chloro-5-hydroxymethylimidazole AC1L2XYV Exp 7711 {2-Butyl-5-chloro-3-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazol-4-yl}-methanol (EXP7711 (IMI)) 4''-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid;H2O BDBM50003399 i4''-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid (1,1'-Biphenyl)-2-carboxylic acid, 4'-((2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)- 4-Chloro-5-hydroxymethyl-3-imidazol-1-ylmethyl-biphenyl-2-carboxylic acid butyl ester CTK0H6905 UUPNFNCKGJOLQE-UHFFFAOYSA-N 2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzoic acid ACMC-20mkt7 EXP-7711 4'-((2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid L001953 114798-27-5 DTXSID60150853 [1,1'-Biphenyl]-2-carboxylicacid, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]- [ Show all ]
Inchi Key	UUPNFNCKGJOLQE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H23ClN2O3/c1-2-3-8-20-24-21(23)19(14-26)25(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(27)28/h4-7,9-12,26H,2-3,8,13-14H2,1H3,(H,27,28)
PubChem CID	130762
ChEMBL	CHEMBL274447
IUPHAR	N/A
BindingDB	50003399
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
346037	Type-1 angiotensin II receptor	P25104	AGTR1	Bos taurus (Bovine)	359
346038	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
346041	Type-1 angiotensin II receptor	Q9WV26	AGTR1	Cavia porcellus (Guinea pig)	359
346042	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
346039	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359
346040	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363
346043	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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