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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Imiloxan
Molecular formula	C14H16N2O2
IUPAC name	2-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-ethylimidazole
Molecular weight	244.294
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	2.1
Synonyms	Tox21_110175 (+-)-2-(1,4-Benzodioxan-2-ylmethyl)-1-ethylimidazole 2-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-1-ethylimidazole AC1Q7014 CCG-204788 DTXSID1045162 Imiloxanum [Latin] NCGC00024917-02 1-ethyl-2-(1,4-benzodioxan-2-ylmethyl)imidazole 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-1-(1-ethyl-1H-imidazol-2-yl)ethanone hydrochloride API0008696 CHEMBL347695 NCGC00015570-03 PDSP1_001499 SCHEMBL757962 2-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-ethyl-1H-imidazole CAS-81167-16-0 DSSTox_GSID_45162 Imiloxano [Spanish] NCGC00015570-06 Tox21_110175_1 (RS)-2-(1,4-Benzodioxan-2-ylmethyl)-1-ethylimidazol 2-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-ethyl-imidazole AKOS028111028 CHEBI:91522 GNF-Pf-2156 L000310 NCGC00024917-03 1H-Imidazole, 2-((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)-1-ethyl-, (7R-(7alpha,8beta,10beta))- BDBM85234 D03IVG Imiloxan [INN] NCGC00015570-04 PDSP2_001483 Tox21 110175 2-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-1-ethyl-1H-imidazole AC1L334I CAS_81167-16-0 DSSTox_RID_80712 Imiloxanum NCGC00015570-07 UXABARREKCJULM-UHFFFAOYSA-N 2-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-ethylimidazole AN-3505 GTPL3470 Lopac0_000703 NSC_133621 RS-21361 1H-Imidazole, 2-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-ethyl- 81167-16-0 BRD-A10903566-003-02-8 DSSTox_CID_25162 Imiloxano NCGC00015570-05 [ Show all ]
Inchi Key	UXABARREKCJULM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H16N2O2/c1-2-16-8-7-15-14(16)9-11-10-17-12-5-3-4-6-13(12)18-11/h3-8,11H,2,9-10H2,1H3
PubChem CID	133621
ChEMBL	CHEMBL347695
IUPHAR	3470
BindingDB	85234
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
347793	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
347794	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
555016	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
347796	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
347792	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446

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