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Ligand

NameNaloxone(-)
Molecular formulaC19H21NO4
IUPAC name4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular weight327.38
Hydrogen bond acceptor5
Hydrogen bond donor2
XlogP2.1
Synonyms12-Allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-4aH-8,9c-iminoethanophenanthro(4,5-bcd)furan-5-one
17-Allyl-4,5-.alpha.-epoxy-3,14-dihydroxymorphinan-6-one
4aH-8,9c-Iminoethanophenanthro(4,5-bcd)furan-5(6H)-one, N-allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-
AC1L1I51
BDBM86260
[ Show all ]
Inchi KeyUZHSEJADLWPNLE-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2
PubChem CID4425
ChEMBLN/A
IUPHARN/A
BindingDB86260
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
349342D(1A) dopamine receptorQ95136DRD1Bos taurus (Bovine)446
349341Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
349339Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
349344Kappa-type opioid receptorP41144OPRK1Cavia porcellus (Guinea pig)380
349340Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
349343Mu-type opioid receptorP97266OPRM1Cavia porcellus (Guinea pig)98
349345Mu-type opioid receptorP79350OPRM1Bos taurus (Bovine)401
556909Mu-type opioid receptorP33535Oprm1Rattus norvegicus (Rat)398
556908Nociceptin receptorP35377Oprl1Mus musculus (Mouse)367

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