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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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Ligand

NameBAM-1303
Molecular formulaC25H25BrN4
IUPAC name(6aR,9R,10aR)-5-bromo-7-methyl-9-[(2-phenylimidazol-1-yl)methyl]-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline
Molecular weight461.407
Hydrogen bond acceptor2
Hydrogen bond donor1
XlogP5.0
Synonyms115219-10-8
BAM 1303
BDBM81773
CAS_115219-10-8
Inchi KeyVKABNRMTNPWHBD-ZWDAVXSWSA-N
Inchi IDInChI=1S/C25H25BrN4/c1-29-14-16(15-30-11-10-27-25(30)17-6-3-2-4-7-17)12-19-18-8-5-9-21-23(18)20(13-22(19)29)24(26)28-21/h2-11,16,19,22,28H,12-15H2,1H3/t16-,19-,22-/m1/s1
PubChem CID10344262
ChEMBLN/A
IUPHARN/A
BindingDB81773
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
356976Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
356977Alpha-2A adrenergic receptorQ28838ADRA2ABos taurus (Bovine)452
356978Alpha-2A adrenergic receptorP18871ADRA2ASus scrofa (Pig)450
356981Alpha-2A adrenergic receptorP22909Adra2aRattus norvegicus (Rat)450
356974Alpha-2B adrenergic receptorO77715ADRA2BDidelphis virginiana (North American opossum)382
356975Alpha-2B adrenergic receptorO77830ADRA2BOryctolagus cuniculus (Rabbit)394
356982Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
462298Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
356979Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
356983Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462

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