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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001171697
Molecular formula	C23H22FN3OS2
IUPAC name	2-[2-(dimethylamino)ethylsulfanyl]-5-(4-fluorophenyl)-6-methyl-3-phenylthieno[2,3-d]pyrimidin-4-one
Molecular weight	439.567
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.6
Synonyms	cid_2460453 Z24750889 2-{[2-(dimethylamino)ethyl]sulfanyl}-5-(4-fluorophenyl)-6-methyl-3-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one MLS-0354500.0001 2-(2-dimethylaminoethylsulfanyl)-5-(4-fluorophenyl)-6-methyl-3-phenylthieno[2,3-d]pyrimidin-4-one AC1M73U5 REGID_for_CID_2460453 2-[2-(dimethylamino)ethylthio]-5-(4-fluorophenyl)-6-methyl-3-phenyl-4-thieno[2,3-d]pyrimidinone HMS2907B20 ZINC3343977 734545-70-1 2-[2-(dimethylamino)ethylsulfanyl]-5-(4-fluorophenyl)-6-methyl-3-phenyl-thieno[2,3-d]pyrimidin-4-one AKOS033923472 CHEMBL1382003 SMR000589497 2-[2-(dimethylamino)ethylthio]-5-(4-fluorophenyl)-6-methyl-3-phenyl-thieno[2,3-d]pyrimidin-4-one MCULE-2427285714 BDBM80039 MolPort-005-874-815 2-[2-(dimethylamino)ethylsulfanyl]-5-(4-fluorophenyl)-6-methyl-3-phenylthieno[2,3-d]pyrimidin-4-one [ Show all ]
Inchi Key	WIQVPSDSSXAQHC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22FN3OS2/c1-15-19(16-9-11-17(24)12-10-16)20-21(30-15)25-23(29-14-13-26(2)3)27(22(20)28)18-7-5-4-6-8-18/h4-12H,13-14H2,1-3H3
PubChem CID	2460453
ChEMBL	CHEMBL1382003
IUPHAR	N/A
BindingDB	80039
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
374355	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
374358	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
374356	C-X-C chemokine receptor type 5	P32302	CXCR5	Homo sapiens (Human)	372
374357	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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