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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1MHY5M
Molecular formula	C26H26N2O3
IUPAC name	(21S)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol
Molecular weight	414.505
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	3.3
Synonyms	(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol BDBM21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol
Inchi Key	WIYUZYBFCWCCQJ-XEWUMVRVSA-N
Inchi ID	InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
PubChem CID	3034754
ChEMBL	N/A
IUPHAR	N/A
BindingDB	21864
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
374609	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
374611	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
374612	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
462428	Delta-type opioid receptor	P79291	OPRD1	Sus scrofa (Pig)	228
374606	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
374608	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
374613	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
374616	Kappa-type opioid receptor	P33534	Oprk1	Mus musculus (Mouse)	380
374607	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
374610	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
374615	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
374617	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398
374614	Neuropeptides B/W receptor type 1	P48145	NPBWR1	Homo sapiens (Human)	328
374618	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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