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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	19(R)-hydroxy-PGE2
Molecular formula	C20H32O6
IUPAC name	(Z)-7-[(1R,2R,3R)-2-[(E,3S,7R)-3,7-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoic acid
Molecular weight	368.47
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	1.3
Synonyms	19(R)-OH-PGE2 9-Oxo-11R,15S,19R-trihydroxy-5Z,13E-prostadienoate NCGC00161298-01 (Z)-7-[(1R,2R,3R)-2-[(E,3S,7R)-3,7-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoic acid BML1-G11 SR-01000946845-1 19R-hydroxy-PGE2 LMFA03010024 19-Hydroxy-PGE2 9-oxo-11R,15S,19R-trihydroxy-5Z,13E-prostadienoic acid SCHEMBL2630490 1279AH 19R-(OH)-PGE2 D05MXO ZINC12495318 19(R)-hydroxy-Prostaglandin E2 64625-54-3 MolPort-027-640-887 19-OH-PGE2 AC1NR1DV SR-01000946845 19(R)-hydroxy Prostaglandin E2 19R-19-Hydroxy PGE-2 GTPL1947 [ Show all ]
Inchi Key	WTJYDBMHYPQFNJ-ZUVVJKHESA-N
Inchi ID	InChI=1S/C20H32O6/c1-14(21)7-6-8-15(22)11-12-17-16(18(23)13-19(17)24)9-4-2-3-5-10-20(25)26/h2,4,11-12,14-17,19,21-22,24H,3,5-10,13H2,1H3,(H,25,26)/b4-2-,12-11+/t14-,15+,16-,17-,19-/m1/s1
PubChem CID	5283038
ChEMBL	N/A
IUPHAR	1947
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555202	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
555203	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
555204	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488

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