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Ligand

NameAM966
Molecular formulaC27H23ClN2O5
IUPAC name2-[4-[4-[4-[[(1R)-1-(2-chlorophenyl)ethoxy]carbonylamino]-3-methyl-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid
Molecular weight490.94
Hydrogen bond acceptor6
Hydrogen bond donor2
XlogP5.6
Synonyms(4'-(4-((R)-1-(2-Chlorophenyl)ethoxycarbonylamino)-3-methylisoxazol-5-yl)biphenyl-4-yl)acetic acid
(4'-{4-[(r)-1-(2-chloro-phenyl)-eth-oxycarbonylamino]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-acetic acid
(R)-2-(4'-(4-(((1-(2-Chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetic acid
1228690-19-4
2-(4-{4-[4-({[(1R)-1-(2-chlorophenyl)ethoxy]carbonyl}amino)-3-methyl-1,2-oxazol-5-yl]phenyl}phenyl)acetic acid
[ Show all ]
Inchi KeyWWQTWEWAPUCDDZ-QGZVFWFLSA-N
Inchi IDInChI=1S/C27H23ClN2O5/c1-16-25(29-27(33)34-17(2)22-5-3-4-6-23(22)28)26(35-30-16)21-13-11-20(12-14-21)19-9-7-18(8-10-19)15-24(31)32/h3-14,17H,15H2,1-2H3,(H,29,33)(H,31,32)/t17-/m1/s1
PubChem CID46240292
ChEMBLCHEMBL3621966
IUPHAR2905
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
384156Lysophosphatidic acid receptor 1Q92633LPAR1Homo sapiens (Human)364
555213Lysophosphatidic acid receptor 1P61793Lpar1Mus musculus (Mouse)364
384157Lysophosphatidic acid receptor 2Q9HBW0LPAR2Homo sapiens (Human)351
555214Lysophosphatidic acid receptor 2Q9JL06Lpar2Mus musculus (Mouse)348
384155Lysophosphatidic acid receptor 3Q9UBY5LPAR3Homo sapiens (Human)353
555212Lysophosphatidic acid receptor 3Q9EQ31Lpar3Mus musculus (Mouse)354
555215Lysophosphatidic acid receptor 4Q99677LPAR4Homo sapiens (Human)370

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