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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AM966
Molecular formula	C27H23ClN2O5
IUPAC name	2-[4-[4-[4-[[(1R)-1-(2-chlorophenyl)ethoxy]carbonylamino]-3-methyl-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid
Molecular weight	490.94
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.6
Synonyms	AJ-115584 C27H23ClN2O5 HY-15277 (R)-2-(4'-(4-(((1-(2-Chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetic acid AM 966 CHEMBL3621966 NCGC00378914-01 EX-A1956 W-5827 (4'-(4-((R)-1-(2-Chlorophenyl)ethoxycarbonylamino)-3-methylisoxazol-5-yl)biphenyl-4-yl)acetic acid AK158794 CEO54NH393 KS-00000SGE 1228690-19-4 AM 966;AM-966 CS-1013 SCHEMBL2292013 2917AH BCP16395 GTPL2905 ZINC65731652 (4'-{4-[(r)-1-(2-chloro-phenyl)-eth-oxycarbonylamino]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-acetic acid AKOS024258999 MolPort-035-690-336 2-(4-{4-[4-({[(1R)-1-(2-chlorophenyl)ethoxy]carbonyl}amino)-3-methyl-1,2-oxazol-5-yl]phenyl}phenyl)acetic acid AM-966 DTXSID10153758 UNII-CEO54NH393 [ Show all ]
Inchi Key	WWQTWEWAPUCDDZ-QGZVFWFLSA-N
Inchi ID	InChI=1S/C27H23ClN2O5/c1-16-25(29-27(33)34-17(2)22-5-3-4-6-23(22)28)26(35-30-16)21-13-11-20(12-14-21)19-9-7-18(8-10-19)15-24(31)32/h3-14,17H,15H2,1-2H3,(H,29,33)(H,31,32)/t17-/m1/s1
PubChem CID	46240292
ChEMBL	CHEMBL3621966
IUPHAR	2905
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
384156	Lysophosphatidic acid receptor 1	Q92633	LPAR1	Homo sapiens (Human)	364
555213	Lysophosphatidic acid receptor 1	P61793	Lpar1	Mus musculus (Mouse)	364
384157	Lysophosphatidic acid receptor 2	Q9HBW0	LPAR2	Homo sapiens (Human)	351
555214	Lysophosphatidic acid receptor 2	Q9JL06	Lpar2	Mus musculus (Mouse)	348
384155	Lysophosphatidic acid receptor 3	Q9UBY5	LPAR3	Homo sapiens (Human)	353
555212	Lysophosphatidic acid receptor 3	Q9EQ31	Lpar3	Mus musculus (Mouse)	354
555215	Lysophosphatidic acid receptor 4	Q99677	LPAR4	Homo sapiens (Human)	370

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