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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3290094
Molecular formula	C31H33ClN4O5
IUPAC name	(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-4-ethylpyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
Molecular weight	577.078
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	6.8
Synonyms	BDBM50019410 SCHEMBL18983529
Inchi Key	WZQNVNSPKOSEAU-MHZLTWQESA-N
Inchi ID	InChI=1S/C31H33ClN4O5/c1-4-20-28(30(37)34-27(31(38)39)18-9-6-5-7-10-18)35-36(23-15-16-33-22-17-19(32)13-14-21(22)23)29(20)26-24(40-2)11-8-12-25(26)41-3/h8,11-18,27H,4-7,9-10H2,1-3H3,(H,34,37)(H,38,39)/t27-/m0/s1
PubChem CID	90644387
ChEMBL	CHEMBL3290094
IUPHAR	N/A
BindingDB	50019410
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
386453	Neurotensin receptor type 1	P20789	Ntsr1	Rattus norvegicus (Rat)	424
386454	Neurotensin receptor type 2	Q63384	Ntsr2	Rattus norvegicus (Rat)	416

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