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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL426629
Molecular formula	C28H33N3O2
IUPAC name	N-[4-[(4aS)-10-methoxy-1,2,4,4a,5,6-hexahydropyrazino[1,2-a]quinolin-3-yl]butyl]naphthalene-2-carboxamide
Molecular weight	443.591
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.2
Synonyms	Naphthalene-2-carboxylic acid [4-((S)-10-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-butyl]-amide BDBM50166022
Inchi Key	XLHPOAMYVQMRPZ-VWLOTQADSA-N
Inchi ID	InChI=1S/C28H33N3O2/c1-33-26-10-6-9-22-13-14-25-20-30(17-18-31(25)27(22)26)16-5-4-15-29-28(32)24-12-11-21-7-2-3-8-23(21)19-24/h2-3,6-12,19,25H,4-5,13-18,20H2,1H3,(H,29,32)/t25-/m0/s1
PubChem CID	11775107
ChEMBL	CHEMBL426629
IUPHAR	N/A
BindingDB	50166022
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
394874	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
394873	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
394875	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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