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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(R)-alpha-Methylhistamine
Molecular formula	C6H11N3
IUPAC name	(2R)-1-(1H-imidazol-5-yl)propan-2-amine
Molecular weight	125.175
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	-0.3
Synonyms	(R)-2-(3H-Imidazol-4-yl)-1-methyl-ethylamine 1H-Imidazole-4-ethanamine, alpha-methyl-, (alphaR)- Alpha Methylhistamine CHEBI:73337 LS-177199 PDSP1_000542 r-alpha-methylhistamine [3H]-R-alpha-Methylhistamine (2R)-1-(1H-imidazol-4-yl)propan-2-amine (R)-[3H]alpha-methylhistamine Alpha-Methylhistane-R D03SAM NCGC00024656-02 PDSP2_000539 SCHEMBL73663 (R)-(-)-4-(2-aminopropyl)imidazole AC1Q299Z C6H11N3 GTPL1237 PDSP1_000535 R(-)-\|A-Methyl-1H-imidazole-5-ethanamine Dihydrochloride ZINC3872814 (R)-alpha-MeHA alpha-methylhistamine, (R)-isomer LS-191796 PDSP2_000507 RAMH (2R)-1-(1H-imidazol-5-yl)propan-2-amine (R)alpha-Me-histamine 75614-87-8 BDBM22904 D04HEZ NCGC00024656-03 R(-)-alpha-METHYLHISTAMINE Tocris-0569 (R)-(-)-alpha-methylhistamine AKOS006343508 CCG-204707 Lopac0_000618 PDSP1_000541 r(-)alpha methylhistamine [3H](R)-alpha-methylhistamine 4491AJ Alpha-Methylhistamine-R CHEMBL268229 NCGC00024656-01 PDSP2_000533 SCHEMBL4155130 (2R)-1-(3H-imidazol-4-yl)propan-2-amine (\|AR)-\|A-Methyl-1H-imidazole-4-ethanamine Dihydrochloride AC1L4GIC BDBM50215536 GTPL1236 NCGC00024656-04 R(-)-\|A-Methyl Histamine Dihydrochloride XNQIOISZPFVUFG-RXMQYKEDSA-N [ Show all ]
Inchi Key	XNQIOISZPFVUFG-RXMQYKEDSA-N
Inchi ID	InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m1/s1
PubChem CID	156615
ChEMBL	CHEMBL268229
IUPHAR	1236, 1237
BindingDB	50215536, 22904
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
396550	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
396551	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
396547	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445
396548	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
396552	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
555270	Histamine H3 receptor	P58406	Hrh3	Mus musculus (Mouse)	445
396549	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
396554	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
555269	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391

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