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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL179861
Molecular formula	C20H19ClN2O
IUPAC name	N-butan-2-yl-1-(2-chlorophenyl)isoquinoline-3-carboxamide
Molecular weight	338.835
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.3
Synonyms	3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-(1-methylpropyl)- SCHEMBL1170339 1-(2-chlorophenyl)-n-(1-methylpropyl)-3-isoquinolinecarboxamide BDBM50180870 124236-61-9 CTK0C2644 ACMC-1C1J3 XXSIYNJKCPZOFQ-UHFFFAOYSA-N 1-(2-CHLOROPHENYL)-N-(1-METHYLPROPYL)-ISOQUINOLINE-3-CARBOXAMIDE 157809-85-3 N-sec-Butyl-1-(2-chlorophenyl)isoquinoline-3-carboxamide 1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinoline carboxamide AKOS030541665 1-[2-chlorophenyl]-N-[1-methyl-propyl]-3-isoquinoline carboxamide [ Show all ]
Inchi Key	XXSIYNJKCPZOFQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19ClN2O/c1-3-13(2)22-20(24)18-12-14-8-4-5-9-15(14)19(23-18)16-10-6-7-11-17(16)21/h4-13H,3H2,1-2H3,(H,22,24)
PubChem CID	11500992
ChEMBL	CHEMBL179861
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
403447	Thyrotropin-releasing hormone receptor	P21761	Trhr	Mus musculus (Mouse)	393

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