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Ligand

Name148672-13-3
Molecular formulaC29H31N5O3
IUPAC nameN-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide
Molecular weight497.599
Hydrogen bond acceptor7
Hydrogen bond donor1
XlogP4.9
Synonyms(1,1'-Biphenyl)-4-carboxamide, N-(4-methoxy-3-(4-methyl-1-piperazinyl)phenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-
01,1'-Biphenyl-4-carboxamide, N-04-methoxy-3-((4-methyl-1-piperazinyl)phenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-
2'-Methyl-4'-(5-methyl-(1,2,4)-oxadiazol-3-yl)biphenyl-4-carboxylic acid (4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)amide
2LLH6CEB40
AC-27423
[ Show all ]
Inchi KeyYDBCEBYHYKAFRX-UHFFFAOYSA-N
Inchi IDInChI=1S/C29H31N5O3/c1-19-17-23(28-30-20(2)37-32-28)9-11-25(19)21-5-7-22(8-6-21)29(35)31-24-10-12-27(36-4)26(18-24)34-15-13-33(3)14-16-34/h5-12,17-18H,13-16H2,1-4H3,(H,31,35)
PubChem CID107780
ChEMBLCHEMBL15928
IUPHAR14
BindingDB79215
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 36
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
4071135-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
4071165-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
4070945-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
4071055-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
4071075-hydroxytryptamine receptor 1BO08892HTR1BCavia porcellus (Guinea pig)389
4070985-hydroxytryptamine receptor 1DP28565Htr1dRattus norvegicus (Rat)374
4070995-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
4071225-hydroxytryptamine receptor 1DQ60484HTR1DCavia porcellus (Guinea pig)376
4071245-hydroxytryptamine receptor 1DQ61224Htr1dMus musculus (Mouse)374
4071105-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
4071215-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
4071155-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5571765-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
4071265-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
4071125-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
4071065-hydroxytryptamine receptor 4O70528HTR4Cavia porcellus (Guinea pig)388
4071085-hydroxytryptamine receptor 4Q13639HTR4Homo sapiens (Human)388
4071025-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
4070935-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
4071175-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479

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