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Ligand

NameAmentoflavone
Molecular formulaC30H18O10
IUPAC name8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Molecular weight538.464
Hydrogen bond acceptor10
Hydrogen bond donor6
XlogP5.0
Synonyms(4-hydroxyphenyl)-4H-chromen-4-one
1617-53-4
3',8''-Biapigenin
3',8-Bi[4',5,7-trihydroxyflavone]
4',4''',5,5'',7,7''-Hexahydroxy-3''',8-biflavone, 8CI
[ Show all ]
Inchi KeyYUSWMAULDXZHPY-UHFFFAOYSA-N
Inchi IDInChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H
PubChem CID5281600
ChEMBLCHEMBL63354
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 5 hydrogen bond donor.
This ligand is heavier than 500 daltons.

Known GPCRs

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Total entries: 28
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
4197665-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
4197905-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
4197735-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
4197765-hydroxytryptamine receptor 1DP79400HTR1DSus scrofa (Pig)291
4197885-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
4197895-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
4197705-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
4197865-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
419777Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
419784Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
419785Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
419792Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
419779Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
419781D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
419771D(1B) dopamine receptorP21918DRD5Homo sapiens (Human)477
419791D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
419775Delta-type opioid receptorP79291OPRD1Sus scrofa (Pig)228
419778Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
419780Glucagon-like peptide 1 receptorP43220GLP1RHomo sapiens (Human)463
419768Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380

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