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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL457873
Molecular formula	C17H21N5O2
IUPAC name	tert-butyl 4-(1-pyridin-4-yltriazol-4-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
Molecular weight	327.388
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	1.4
Synonyms	BDBM50273897 SCHEMBL2891855 YZMQBHNRNAXMLR-UHFFFAOYSA-N tert-butyl 4-[1-(pyridin-4-yl)-1H-[1,2,3]triazol-4-yl]-1,2,3,6-tetrahydropyridine-1-carboxylate tert-Butyl-4-[1-pyridin-4-yl-1 H-1,2,3-triazol-4-yl]-3,6-dihydropyridine-1(2H)-carboxylate
Inchi Key	YZMQBHNRNAXMLR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21N5O2/c1-17(2,3)24-16(23)21-10-6-13(7-11-21)15-12-22(20-19-15)14-4-8-18-9-5-14/h4-6,8-9,12H,7,10-11H2,1-3H3
PubChem CID	44588462
ChEMBL	CHEMBL457873
IUPHAR	N/A
BindingDB	50273897
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
423081	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
423083	Metabotropic glutamate receptor 1	P97772	Grm1	Mus musculus (Mouse)	1199
423082	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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