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Check the ligand table for details.
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Ligand

Name	trifluoperazine
Molecular formula	C21H24F3N3S
IUPAC name	10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
Molecular weight	407.499
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	5.0
Synonyms	10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE IDI1_002190 117-89-5 KBio2_003098 AB00053558 KBio3_002148 AN-22776 KSC-210-031 Bio1_001436 MLS001146870 BRD-K89732114-001-05-9 NCGC00013226-02 Calmazine NCGC00013226-10 cid_5566 EINECS 204-219-4 10-(3-(4-methylpiperazin-1-yl)propyl)-2-(trifluoromethyl)-10H-phenothiazine GTPL214 Stelazine (Dihydrochloride) Terfluzine (TN) Trifluoromethylperazine Triftazine NCGC00024251-04 UNII-214IZI85K3 NCIStruc2_001093 PDSP2_001284 QTL1_000085 SPBio_002525 HMS1990L11 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine KB-217586 KBio2_005666 AB00053558_29 KBioGR_000835 AX8155275 Lopac-T-8516 Biomol-NT_000060 Modalina BSPBio_000306 NCGC00013226-05 CCRIS 6994 NCGC00013226-13 D0R4OM 10-(.gamma.-(N'-Methylpiperazino)propyl)-2-trifluoromethylphenothiozine Eskazinyl (TN) 10-(gamma-(N'-Methylpiperazino)propyl)-2-trifluoromethylphenothiazine Stelazine Concentrate Trifluoperazin Trifluoperazine hydrochloride Trifluperazine Tripfluoperazine Hydrochloride NCGC00024251-07 NSC 17474 PMS Trifluoperazine SC-95890 Spectrum4_000368 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine # HSDB 3195 10H-Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)- KBio2_001148 5858-EP2309505A1 KBio3_000959 AJ-73370 KBioSS_001148 Bio1_000458 M989 BRD-K89732114-001-02-6 MRF-0000088 C07168 NCGC00013226-08 CHEMBL422 DivK1c_000843 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-phenothiazine Flurazine SR-01000003020-6 Synklor (Salt/Mix) Trifluoperazina [INN-Spanish] Trifluoperazinum [INN-Latin] Triftazin Triphthasine NCI60_004087 NSC17474 Prestwick2_000313 SMR001566649 HMS1362L11 10-[3-(4-methylpiperazin-1-yl)-propyl]-2-trifluoromethylphenothiazine Jatroneural (Salt/Mix) 2-Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine KBio2_003716 AB00053558-27 KBio3_002910 Apo-Trifluoperazine KUC109776N Bio2_000435 MLS002702821 BRD-K89732114-300-05-5 NCGC00013226-03 CAS-440-17-5 NCGC00013226-11 cMAP_000048 Eskazine 10-(gamma-(n inverted exclamation mark -methylpiperazino)propyl)-2-trifluoromethylphenothiazine Stelazine (Salt/Mix) TFP Trifluoperazine (INN) Trifluoroperazine Triftazine (Salt/Mix) NCGC00024251-05 ZEWQUBUPAILYHI-UHFFFAOYSA-N NINDS_000843 Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)- RP 7623 Spectrum2_000828 HMS2089J11 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride KBio1_000843 214IZI85K3 KBio2_006284 AC1L1KMT KBioGR_002431 BDBM79181 Lopac0_001232 BPBio1_000338 Modalina (TN) BSPBio_001190 NCGC00013226-06 CHEBI:45951 NCGC00013226-15 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine Fluoperazine 10-(gamma-(N'-Methylpiperazino)propyl)-2-trifluoromethylphenothiozine Stellazine Trifluoperazin HCl Trifluoperazine [INN:BAN] Triflurin Triphtazin NCI17474 NSC 46061 Prestwick0_000313 SCHEMBL24866 Spectrum5_001553 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride IDI1_000843 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)- KBio2_002431 KBio3_000960 AKOS001487920 KBioSS_002437 Bio1_000947 MCULE-3726407978 BRD-K89732114-001-03-4 NCGC00013226 C21H24F3N3S NCGC00013226-09 cid_2913535 DTXSID1046928 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine FT-0650159 Stelazine Terfluzine (Salt/Mix) Trifluoperazina [Italian] Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine Triftazin (Salt/Mix) NCGC00024251-03 Triphthazine (Salt/Mix) NCIStruc1_001127 PDSP1_001300 Prestwick3_000313 SPBio_000755 HMS1792L11 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine Jatroneural (TN) 2-Trifluoromethyl-10-[3'-(1-methyl-4-piperazinyl)propyl]phenothiazine KBio2_004999 AB00053558_28 KBioGR_000530 Apo-trifluoperazine (TN) L001075 Bio2_000915 MLS006011857 BRD-K89732114-300-07-1 NCGC00013226-04 CCG-37306 NCGC00013226-12 D08636 Eskazine (TN) 10-(gamma-(n inverted exclamation mark -methylpiperazino)propyl)-2-trifluoromethylphenothiozine Stelazine (TN) Trifluoperaz (TN) Trifluoperazine HCl Trifluoroperazine dihydrochloride Triperazine NCGC00024251-06 ZINC19418959 Novo-Trifluzine Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)- SBI-0051199.P003 Spectrum3_001374 HMS3429O07 10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride KBio2_000530 5858-EP2302003A1 KBio2_007567 AC1Q3ZYE KBioSS_000530 BIDD:PXR0132 LS-105595 BPBio1_001345 MolPort-001-727-956 BSPBio_002928 NCGC00013226-07 DB00831 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-phenothiazin Fluoperazine (Salt/Mix) 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine Spectrum_000668 STK182873 Trifluoperazina Trifluoperazinum Trifluroperizine Triphtazine NCI60_001427 NSC-17474 Prestwick1_000313 SKF 5019 [ Show all ]
Inchi Key	ZEWQUBUPAILYHI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3
PubChem CID	5566
ChEMBL	CHEMBL422
IUPHAR	214
BindingDB	79181
DrugBank	DB00831
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
426736	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
426749	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
426732	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
557240	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
426730	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
426752	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
426731	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
426739	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
426741	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
426743	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
557243	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
426727	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
557241	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
426745	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
426747	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
426753	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
426734	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
426737	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
515497	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
426728	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443