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Ligand

NameNaltriben
Molecular formulaC26H25NO4
IUPAC name(1S,2S,13R,21R)-22-(cyclopropylmethyl)-11,14-dioxa-22-azaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol
Molecular weight415.489
Hydrogen bond acceptor5
Hydrogen bond donor2
XlogP3.6
Synonyms(5R,12cS)-15-Cyclopropylmethyl-4,5-dihydro-11bbetaH-5beta,12c-(iminoethano)naphtho[2,3-b:1,8,7-b'c'd']bisbenzofuran-1,5abeta(6H)-diol
111555-58-9
4,8-Methano-5H-bisbenzofuro(3,2-e:2',3'-g)isoquinoline-1,8a(9H)-diol, 7-(cyclopropylmethyl)-6,7,8,14b-tetrahydro-, (8R-(4bS*,8alpha,8beta,14bbeta))-
AB00691672-07
BDBM82552
[ Show all ]
Inchi KeyZHVWWEYETMPAMX-IFKAHUTRSA-N
Inchi IDInChI=1S/C26H25NO4/c28-18-8-7-15-11-20-26(29)12-17-16-3-1-2-4-19(16)30-22(17)24-25(26,21(15)23(18)31-24)9-10-27(20)13-14-5-6-14/h1-4,7-8,14,20,24,28-29H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1
PubChem CID5486827
ChEMBLCHEMBL100940
IUPHAR1640
BindingDB82552
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
428902Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
428905Delta-type opioid receptorP32300Oprd1Mus musculus (Mouse)372
428907Delta-type opioid receptorP33533Oprd1Rattus norvegicus (Rat)372
462858Delta-type opioid receptorP79291OPRD1Sus scrofa (Pig)228
428901Kappa-type opioid receptorP41144OPRK1Cavia porcellus (Guinea pig)380
428903Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
428904Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
428906Mu-type opioid receptorP97266OPRM1Cavia porcellus (Guinea pig)98

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