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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BW 245C
Molecular formula	C19H32N2O5
IUPAC name	7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid
Molecular weight	368.474
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.9
Synonyms	4-Imidazolidineheptanoic acid, 3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxo- AC1L3OKB CHEBI:131502 HMS3369D02 ZIDQIOZJEJFMOH-UHFFFAOYSA-N (4S)-(3-[(3R,S)-3-Cyclohexyl-3-hydroxypropyl]-2,5-dioxo)-4-imidazolidine-heptanoic acid 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin AKOS030549066 CTK2H7632 MLS002172471 3-(3-Cyclohexyl-3-hydroxypropyl)-2,5-dioxo-(R,S)-(+/-)-4-imidazolineheptanioc acid 72814-32-5 BW245C GTPL1878 SCHEMBL9488992 4-Imidazolidineheptanoicacid, 3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxo- AC1Q5W5W L000151 7-(3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl)heptanoic acid D0R9CC NCGC00015170-03 3-(3-Cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidine-4-heptanoic acid 75693-75-3 C-28736 HMS2235D12 SMR000058929 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl) hydantoin AC1Q77DO CHEMBL575504 MLS000028690 7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid BW-245C EINECS 278-291-0 REGID_for_CID_119304 [ Show all ]
Inchi Key	ZIDQIOZJEJFMOH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H32N2O5/c22-16(14-8-4-3-5-9-14)12-13-21-15(18(25)20-19(21)26)10-6-1-2-7-11-17(23)24/h14-16,22H,1-13H2,(H,23,24)(H,20,25,26)
PubChem CID	119304
ChEMBL	CHEMBL575504
IUPHAR	1878
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
515802	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
429090	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
429087	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
555417	Prostaglandin D2 receptor	Q9R261	Ptgdr	Rattus norvegicus (Rat)	357
555418	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
429086	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
429088	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
429092	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
429089	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
429094	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359

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