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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL606792
Molecular formula	C17H20FN5
IUPAC name	14-fluoro-6-piperazin-1-yl-3,5-diazatricyclo[9.4.0.02,7]pentadeca-1(11),2(7),3,5,12,14-hexaen-4-amine
Molecular weight	313.38
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.3
Synonyms	2,4-diamino-5,6-disubstituted pyrimidine, 13 CHEMBL523225 14-fluoro-6-(piperazin-1-yl)-3,5-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine BDBM26399
Inchi Key	ZKRHBPHZPPNOHI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H20FN5/c18-12-5-4-11-2-1-3-13-15(14(11)10-12)21-17(19)22-16(13)23-8-6-20-7-9-23/h4-5,10,20H,1-3,6-9H2,(H2,19,21,22)
PubChem CID	25128824
ChEMBL	CHEMBL523225
IUPHAR	N/A
BindingDB	26399
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
430876	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
430877	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
430878	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391

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