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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	12(S)-HETE
Molecular formula	C20H32O3
IUPAC name	(5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid
Molecular weight	320.473
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.2
Synonyms	12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID D0Z5QA LMFA03060007 (12S)-12-hydroxy-5,8,14-cis-10-trans-eicosatetraenoic acid (5Z,8Z,10E,14Z)-(12S)-12-Hydroxyeicosa-5,8,10,14-tetraenoic acid 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid, ~100 mug/mL in ethanol, >=95% (HPLC) 12S-HETE BSPBio_001299 HMS1361A21 NCGC00161240-02 1166AH 12(S)-Hydroxyeicosatetraenoic acid CHEMBL1526258 HMS3402A21 ZINC4655428 12(S)-Hydroxy (5Z,8Z,10E,14Z)-Eicosatetraenoic Acid 12-Hydroxyeicosatetraenoic acid AC1NR1NB GTPL3404 MFCD00036916 (5Z,8Z,10E,12S,14Z)-12-hydroxyeicosa-5,8,10,14-tetraenoic acid (5Z,8Z,10E,14Z)-(12S)-12-Hydroxyicosa-5,8,10,14-tetraenoic acid 12(S)-hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid C14777 HMS1791A21 NCGC00161240-03 12 hete 12-Hete 54397-83-0 D0D5EX IDI1_033769 [S-(E,Z,Z,Z)]-12-Hydroxy-5,8,10,14-eicosatetraenoic Acid 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid 12-L-Hydroxy-5,8,10,14-eicosatetraenoic acid BML1-B07 GTPL5508 NCGC00161240-01 (5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid (S)-12-HETE 12(S)-hydroxy-5,8,14(Z),10(E)-eicosatetraenoic acid 12S-[3H]HETE CHEBI:34146 HMS1989A21 SCHEMBL1242004 [ Show all ]
Inchi Key	ZNHVWPKMFKADKW-LQWMCKPYSA-N
Inchi ID	InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m0/s1
PubChem CID	5283155
ChEMBL	N/A
IUPHAR	5508, 3404
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555429	12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor	F8VQN3	Gpr31	Mus musculus (Mouse)	319
555430	Leukotriene B4 receptor 2	Q9NPC1	LTB4R2	Homo sapiens (Human)	358

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