Detailed GPCR-I-TASSER Statistics for P43088

Submitted Sequence

>sp|P43088|PF2R_HUMAN
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
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Sequence MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
Prediction CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHSSSSSSSSSCCCSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 96888898899987677888643110699999999999999999999997785662058998722899999999999999999889999999727940254897463455999999999999999999999989992063523568356355655779999999999887668836999789449947289975267889788999999999999999999999999997711355410007899999999899999999989999999999976877767305999999999999998599999349999999999988755888767667888775788735666899998899999

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
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Sequence MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
Prediction 46163444333334322332223322100011123213313322330110000023436344301000000000200020023113200000023230221220220002001010211210120000002000000000122343033310000000001200200210100002122233100000103345312100000101311321021013012100100131244345454434311200000000010011013101200000002333332212010100200020003002000001430041014002300324335463344433444444443454446564667

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sec.Str
Seq		CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHSSSSSSSSSCCCSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
14zwjA 0.15 0.15 0.97 2.52Download PFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQH-KKLRTPLN----YILLNLAVADLFMVLGGFTSTLYTSLHG----YFVFGPTGCNLQGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQGSCF-GPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKIFKKVSRDKSVTIYLGKRDYVDHVSQVEPDPELVKG
24bwbA 0.13 0.16 0.82 3.91Download -------------NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNGVTLFTL-------AQSLQSRVDYYLGSLALSDLLILLFALPVDLYNFIWVHH--PWAFGDAGCKGYYFLREACTYATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGLVCT--PIVDTATLRVVIQLNTFMSFLFPMLVASILNTVAARRLTVM-----VEPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLMFVYISDEQWTTHYFYMLSNALVYVSAAINPILYNLVSANFRQVFLSTLACLC------------------------------------
32z73A 0.14 0.18 0.94 3.53Download ETWWYNPSIVVHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKT-KSLQTP----ANMFIINLAFSDFTFSLVNGPLMTISCFLK----KWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWV-TPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLT-CCQFDDKETEDDKDAETEIPAGE-----------
42ziy 0.16 0.20 0.97 1.55Download DLRDNETWWYNPSIIVEFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTK-TKSLQ----TPANMFIINLAFSDFTFSLVNFPLMTISC-FLKKWI---FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLE-WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIP--AGESSDAAPSADA
52ziy 0.13 0.20 0.97 1.17Download -DLRDNETWWYNPSIREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQ-----TPANMFIINLAFSDFTFSLVGFPLMTISCFLK----KWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPL-EWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVCCQFDDKETEDDKDAETEIPAGESSDAAPSADAAQMK
62ziyA 0.14 0.20 0.97 2.91Download ETWWYNPSIIVHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKT-KSLQTP----ANMFIINLAFSDFTFSLVNGPLMTISCFLK----KWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWV-TPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIPAGESSDAAPSADAAQ
73uon 0.13 0.18 0.77 1.68Download ---------------------------FIVLVAGSLSLVTIIGNILVMVSIKVN---RHLQ--TVNNYFLFSLACADLIIGVFSMNLYTLYTV-IGY---WPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVVEDGECYIQFFS----NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIEGDAYPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPC--IPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL----------------------------------------
81u19A 0.16 0.19 0.93 4.58Download FS-NKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQH-----KKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHG----YFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM-SNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHENNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFG-PIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLC--CGKNPLGDD--EASTTVSKTETSQVAPA---------
92ziyA 0.13 0.20 0.97 2.55Download LRDNETPSIIVHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKT-KSLQTP----ANMFIINLAFSDFTFSLVNFPLMTISCFLK----KWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPL-EWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIPAGESSDAAPSADAAQ
104ww3A 0.14 0.18 0.94 3.11Download ETWWYNPSIVVHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKT-KSLQTPAN----MFIINLAFSDFTFSLVNGFPLMTISC---FLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPL-EWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAET-------EIPAGE-----
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.68 (Read more about C-score)
  • Estimated TM-score = 0.81±0.09
  • Estimated RMSD = 5.1±3.3Å

  • Download Model 2
  • C-score = -2.72

  • Download Model 3
  • C-score = -2.62

  • Download Model 4
  • C-score = -4.11

  • Download Model 5
  • C-score = -4.41


    • [Click on P43088_results.tar.bz2 to download the tarball file including all modeling results listed on this page]