Detailed GPCR-I-TASSER Statistics for Q8NGD5

Submitted Sequence

>sp|Q8NGD5|OR4KE_HUMAN
MDPQNYSLVSEFVLHGLCTSRHLQNFFFIFFFGVYVAIMLGNLLILVTVISDPCLHSSPM
YFLLGNLAFLDMWLASFATPKMIRDFLSDQKLISFGGCMAQIFFLHFTGGAEMVLLVSMA
YDRYVAICKPLHYMTLMSWQTCIRLVLASWVVGFVHSISQVAFTVNLPYCGPNEVDSFFC
DLPLVIKLACMDTYVLGIIMISDSGLLSLSCFLLLLISYTVILLAIRQRAAGSTSKALST
CSAHIMVVTLFFGPCIFVYVRPFSRFSVDKLLSVFYTIFTPLLNPIIYTLRNEEMKAAMK
KLQNRRVTFQ

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |          
Sequence MDPQNYSLVSEFVLHGLCTSRHLQNFFFIFFFGVYVAIMLGNLLILVTVISDPCLHSSPMYFLLGNLAFLDMWLASFATPKMIRDFLSDQKLISFGGCMAQIFFLHFTGGAEMVLLVSMAYDRYVAICKPLHYMTLMSWQTCIRLVLASWVVGFVHSISQVAFTVNLPYCGPNEVDSFFCDLPLVIKLACMDTYVLGIIMISDSGLLSLSCFLLLLISYTVILLAIRQRAAGSTSKALSTCSAHIMVVTLFFGPCIFVYVRPFSRFSVDKLLSVFYTIFTPLLNPIIYTLRNEEMKAAMKKLQNRRVTFQ
Prediction CCCCCCCSSSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHSSSSSCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCSSCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCSSSSSCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCC
Conf.Score 9987887005888926999822589999999999999998788736634517877999819987659988664333360999998716996783899999999999999999999999986518874721025221787599999999999999999999999532899898836777518388787840340644544777777999999999999999999995113731221999898879993315630544688588999973133478886156400027433562999999999997127679

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |          
Sequence MDPQNYSLVSEFVLHGLCTSRHLQNFFFIFFFGVYVAIMLGNLLILVTVISDPCLHSSPMYFLLGNLAFLDMWLASFATPKMIRDFLSDQKLISFGGCMAQIFFLHFTGGAEMVLLVSMAYDRYVAICKPLHYMTLMSWQTCIRLVLASWVVGFVHSISQVAFTVNLPYCGPNEVDSFFCDLPLVIKLACMDTYVLGIIMISDSGLLSLSCFLLLLISYTVILLAIRQRAAGSTSKALSTCSAHIMVVTLFFGPCIFVYVRPFSRFSVDKLLSVFYTIFTPLLNPIIYTLRNEEMKAAMKKLQNRRVTFQ
Prediction 8666242200000000004244001000131333233233323300000200330312000100230012001100000020000002532100050000000110331131020002003100000022110100013310000012013102201300131023030000122000100221003000020230003002301310231033133112100200132046122200100300210030232101000000333233011000310331033113000020540230033014430538

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |          
Sec.Str
Seq		CCCCCCCSSSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHSSSSSCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCSSCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCSSSSSCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCC
MDPQNYSLVSEFVLHGLCTSRHLQNFFFIFFFGVYVAIMLGNLLILVTVISDPCLHSSPMYFLLGNLAFLDMWLASFATPKMIRDFLSDQKLISFGGCMAQIFFLHFTGGAEMVLLVSMAYDRYVAICKPLHYMTLMSWQTCIRLVLASWVVGFVHSISQVAFTVNLPYCGPNEVDSFFCDLPLVIKLACMDTYVLGIIMISDSGLLSLSCFLLLLISYTVILLAIRQRAAGSTSKALSTCSAHIMVVTLFFGPCIFVYVRPFSRFSVDKLLSVFYTIFTPLLNPIIYTLRNEEMKAAMKKLQNRRVTFQ
13emlA 0.22 0.22 0.88 3.36Download --------------------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQN-VTNYFVVSLAAADIAVGVLAIPFAITIS---GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVPMNYMVYFN-----------FFACVLVPLLLMLGVYLRIFLAARQLVHAAKSLAIIVGLFALCWLPLH-IINCFTFFCPDCSHAWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
25tgzA 0.19 0.23 0.90 2.34Download -RGENFMDIECF----MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVL--------PLLGWNCEKL---------QSVCSDIFHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARELAKTLVLILVVLIICWGPLLAIMVKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM--------
35tgzA 0.17 0.23 0.88 2.08Download ----------GGRGENFMDIPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKD-SRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLCEKLQSVC-------------------SDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHQARMDIELAKTLVLILVVLIICWGPLLAIMVGKMNLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-------
44djh 0.15 0.27 0.90 1.55Download -------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKM-KTATNIYIFNLALADALVTT-TMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVR---EDVDVIECSLQFPDD---DYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSLSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-----
54yay 0.15 0.23 0.91 1.23Download LKTTRNAYIQKYLILNSSDCNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKT-VASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFF-------IITVCAFHYE--------TLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK-----KNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLL-------
65tgzA 0.18 0.23 0.91 3.58Download GRGENFMDIECFMVLN----PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAV--------LPLLGWNCEK--------LQSVCSDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQAIELAKTLVLILVVLIICWGPLLAIMVYDVFLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-------
74iaq 0.21 0.25 0.85 1.74Download --------------------LPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLH-TPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFW-RQASECVVNT-----------------D---HILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADRERKATKTLGIILGAFIVCWLPFFIISLVMPIH-LAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK----
84ea3A 0.21 0.23 0.82 2.92Download -------------------PLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKT-ATNIYIFNLALADTLVLLT-LPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPTSSKAQAVNVAIWALASVVGVPVAIMGSAQ----------VEDEEIECLVEIP----------TPQDYWGPVFAICIFLFSFLVISVCYSLMIRRLRGVRLLSGSAVFVGCWTPVQVFVLAQGLG----VQPSSTAVAILRFCTALGYVNSCLNPILYAFLDENFKACFR----------
95tgzA 0.18 0.23 0.90 4.76Download GRGENFMDIECFMVL----NPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF-HRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLG---------NCEK---------LQSVCSDIFHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQAIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-------
102ydoA 0.20 0.23 0.92 5.40Download -----------------------SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQN-VTNYFVVSAAAADILVGVLAIPFAIA--ISTGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQKQMESTLQKEVHAAKSLAIIVGLFALCCFTFFCPDCSHAPLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.05 (Read more about C-score)
  • Estimated TM-score = 0.72±0.11
  • Estimated RMSD = 6.2±3.8Å

  • Download Model 2
  • C-score = -2.26

  • Download Model 3
  • C-score = -0.03

  • Download Model 4
  • C-score = -2.76

  • Download Model 5
  • C-score = -3.22


    • [Click on Q8NGD5_results.tar.bz2 to download the tarball file including all modeling results listed on this page]