GPCR-I-TASSER results for Q8TDT9

[Click on Q8TDT9_results.tar.bz2 to download the tarball file including all modeling results listed on this page]

  Submitted Sequence

>Q8TDT9
MYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLM
YFIGFLLGDSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITW
FLAAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDAS
RYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVP
LVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQVKAITWIMSLFTFNVENVSWKYT
CHGCKS

  Predicted Secondary Structure

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |      
MYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQVKAITWIMSLFTFNVENVSWKYTCHGCKS
PredictionCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCSSSSSCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHSSSSSSSCCCCCC
Conf.Score988888999999999999999999999999999836510368357999999999999999999980798776676544334333024678898558999999999999999999999899987631566135888889999999998899999999500001687787569843767889999999899999999999999999981027753476003678999999999999999999999999999888526679998764524457899971789999999999876714578885463579

  Predicted Solvent Accessibility

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |      
MYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQVKAITWIMSLFTFNVENVSWKYTCHGCKS
Prediction631377124002100021012002102301000102353142131000000001210010100100233413034344434334233433442200010122110110020000000110110013324343044212100000023023300000012313444221100002233300110133232111331220231000000302531466643352034002210120112323332110000001223630341135440663434112203013201211011230010000233168
Values range from 0 (buried residue) to 9 (highly exposed residue)

   Predicted normalized B-factor


  Top 10 templates used by GPCR-I-TASSER

Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |      
Sec.Str
Seq		CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCSSSSSCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHSSSSSSSCCCCCC
MYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQVKAITWIMSLFTFNVENVSWKYTCHGCKS
14n4wA 0.25 0.29 0.99 3.91Download -LFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRL-GEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSES-KINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSYVLCQADCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLL-
24jkvA 0.25 0.29 0.98 2.20Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSRYPAVILFYVNACFFVGSIGWLAQFMARREIVCRADG---TMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTYQPGKTS--YFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYQANCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLI
34jkvA 0.25 0.29 0.99 2.22Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIV-CRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKA-LGTTYQPGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLNCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLI
44o9rA 0.28 0.30 0.94 7.79Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRSNRYPAVILFYVNACFFVGSIGWLAQFMDGREIVCRADGT-MRLGEP--TSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSF----------GKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHADEGLAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYLCQAN----PIPSEKINLFAMFG-TGIAMSTWVWTKATLLI
54o9rA 0.27 0.30 0.96 5.62Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRSNRYPAVILFYVNACFFVGSIGWLAQFMDGREIVCRADGTMRL---GEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSF----------GKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHADLGLAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYLCPDCEKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLI
64jkvA 0.25 0.29 0.99 3.22Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCR-ADGTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGT-TYQPGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYQANCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLI
74o9rA 0.29 0.30 0.95 8.26Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRSNRYPAVILFYVNACFFVGSIGWLAQFMDGRREIVCRADGTMRLG--EPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSF----------GKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHADEGLAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDY--PDCEINRPSLLEKINLFAM-FGTGIAMSTWVWTKATLL-
84o9rA 0.28 0.28 0.94 3.76Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSRYPAVILFYVNACFFVGSIGWLAQFMDGREIVCRADGTMRLGEPT---SNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKGKTS---------YFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHAAS-----KINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLI
94jkvA 0.25 0.29 0.99 2.64Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIV-CRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKAL-GTTYQPGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLNCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLI
104jkvA 0.25 0.29 0.99 3.52Download PLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLG-EPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFK-ALGTTYQPGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLNCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLI
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: FFAS-3D   2: SPARKS-X   3: MUSTER   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: PROSPECT2   

  Top 5 Models predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=1.48 (Read more about C-score)
  • Estimated TM-score = 0.92±0.06
  • Estimated RMSD = 3.3±2.3Å




    •  Please cite following articles when you use the GPCR-I-TASSER server:
    J Zhang, J Yang, R Jang, Y Zhang. Hybrid structure modeling of G protein-coupled receptors in the human genome, submitted (2015).