GPCR-I-TASSER results for Q9GZP7

[Click on Q9GZP7_results.tar.bz2 to download the tarball file including all modeling results listed on this page]

  Submitted Sequence

>Q9GZP7
MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGI
LGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTG
CKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLLCWAPHV
LMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWASG
SMVFFLYRHKQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTVVA
NPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP

  Predicted Secondary Structure

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |             
MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGILGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTGCKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLLCWAPHVLMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWASGSMVFFLYRHKQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTVVANPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP
PredictionCCCHHHHHHHHHHHHHHHHCSSCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCSSSSSSSSSHHHCCCHHHHHHHHHHHHCSSSCCCCHHHHHHHHHCCCSSCHHHHHHHHHHHHHHCCSSSSSSCCCCCCCCCCCCCCSSSSSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHCCHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHCCCCCCCCSSSCC
Conf.Score97514556325677456520325886007756766777877689999999999999999999999999999999817888968999999999999999998489999997463148987579999982572611278999998853099758954876645645867708889999999998556469997288660045321353721645558999999999999999999999999999999998678652533899999988799999999999999999998889999999991689810100999996421464857753589418899999818678999836179

  Predicted Solvent Accessibility

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |             
MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGILGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTGCKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLLCWAPHVLMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWASGSMVFFLYRHKQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTVVANPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP
Prediction63332131011021301000013264431463444144630302200110103310331331122003100000025333110000010013101110201221100000033111312100000000000112000000000020000000322202302220110001300110001020203000102033333233333210000012333010000001013112110000000000000011123102202334224333113200000000001002102210000000120334200000001020010010000000021420120020023343411300026
Values range from 0 (buried residue) to 9 (highly exposed residue)

   Predicted normalized B-factor


  Top 10 templates used by GPCR-I-TASSER

Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |             
Sec.Str
Seq		CCCHHHHHHHHHHHHHHHHCSSCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCSSSSSSSSSHHHCCCHHHHHHHHHHHHCSSSCCCCHHHHHHHHHCCCSSCHHHHHHHHHHHHHHCCSSSSSSCCCCCCCCCCCCCCSSSSSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHCCHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHCCCCCCCCSSSCC
MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGILGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTGCKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLLCWAPHVLMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWASGSMVFFLYRHKQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTVVANPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP
14grvA 0.14 0.15 0.79 1.98Download --------------------------------NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLF----TLARKSLQSTVHYHLGSLALSDLLILLL-AMPVELYNFIWVHHFGDAGCRGYYFLRDACTYATALNVASLSVARYLAIC---HPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLT------------VMSGSVQALRHGVLVARAVVIAFVVCWLPYHVRRLMFCYISDEQWYFYMLTNALAYASSAINPILLVSANFR----------------------
24n6hA 0.12 0.16 0.82 1.36Download --------------------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMK---TATNIYIFNLALADALATST--LPFQSAKYLMETWFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVHPVKALDFR----TPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-------AVVCMLQFPYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVR------LLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG--------
34grvA 0.14 0.15 0.80 1.07Download --------------------------------NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLAR-----KSLQTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHAFGDAGCRGYYFLRDACTYATALNVASLSVARYLAIHPFKAKT----LMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVM-------------GSVQALRHGVLVARAVVIAFVVCWLPYHVRRLMFCYISDEQWYFYMLTNALAYASSAINPILYNLVSANFRQV------------------
42rh1A 0.11 0.21 0.81 2.53Download ----------------------------------------DEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK---FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAISPFKYQ----SLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQ------EAINCYAEETDFFTAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLNIFEMLRIWDAYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFRIAFQELL-------------
52z73A 0.13 0.20 0.91 1.93Download -------------------ETWWYNPSIVVHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTK---TKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGPMAASK----KMSHRRAFIMIIFVWLWSVLWAIGPIFGWG---A---YTLEGVLCNCSFDYIDSTTRNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKEANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKE
64grvA 0.13 0.15 0.80 1.56Download --------------------------------NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLAR----KSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWHPWAFGDAGCRGYYFLRDACTYATALNVASLSVARYLAIC---HPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMSG------------SVQALRHGVLVARAVVIAFVVCWLPYHVRRLMFCYISDEQHYFYMLTNALAYASSAINPILYNLVSANFRQV------------------
74iarA 0.12 0.18 0.81 2.85Download ---------------------------------YIYQDSISLPWKVLLVMLLALITLATTLSNAFVIAT---VYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRT---PKRAAVMIALVWVFSISISLPPFF-WRQ-A------S-----ECVVNTD--HILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDDEDDSQKYLAARERKATKTLGIILGAFIVCWLPFFIISLVMPI--WFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK----------
84buoA 0.15 0.19 0.80 1.94Download --------------------------------NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTL----FTLARKKSLSTVDYYLGSLALSDLLILLL-AMPVELYNFIWVWAFGDAGCRGYYFLRDACTYATALNVVSLSVELYLAICH------PFKAKTLMSTKKFISAIWLASALLAIPTMGLQNLSGDGTHP----GGLVCTPIVDATLKVVIQVNTFMSFLFPMLVASILNTVIANKLTVMVHQ---------PGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWYFYMLTNALVYVSAAINPILYNLVSANFRQVFLSTL-------------
94grvA 0.14 0.15 0.80 1.32Download --------------------------------NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLA-----RKSLQTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHAFGDAGCRGYYFLRDACTYATALNVASLSVARYLAIHPFKAK-----LMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVM------------SGSVQALRHGVLVARAVVIAFVVCWLPYHVRRLMFCYISDEQWYFYMLTNALAYASSAINPILYNLVSANFRQV------------------
103a6pA 0.07 0.19 0.94 1.58Download AMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEKEKCPICVPCGLRLAVRHFGLQILEHVVKSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWLIELDTLSKQGE---------------TQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQEAGYIDWVSMSHITAENCKLLEILCLLLNELQLGAAECLLIAVRKPLMVLFGDVHYILSAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCFGKYLESFLAFTTHPS------QFLRSSTQMTWGALFLLAIIPKYLRASMTNLVKMGFPSKTDSPS
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: FFAS-3D   2: SPARKS-X   3: MUSTER   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: PROSPECT2   

  Top 5 Models predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-1.77 (Read more about C-score)
  • Estimated TM-score = 0.50±0.15
  • Estimated RMSD = 10.6±4.6Å

  • Download Model 2
  • C-score = -2.22

  • Download Model 3
  • C-score = -2.10

  • Download Model 4
  • C-score = -2.81

  • Download Model 5
  • C-score = -2.18




    •  Please cite following articles when you use the GPCR-I-TASSER server:
    J Zhang, J Yang, R Jang, Y Zhang. Hybrid structure modeling of G protein-coupled receptors in the human genome, submitted (2015).