Home Research Services Publications People Teaching Job Opening News Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MUSTER SEGMER FG-MD ModRefiner REMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM

TM-score TM-align MMalign NWalign EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot I-TASSER-MR NeBcon

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW HPSF CASP7 CASP8 CASP9 CASP10 CASP11 CASP12


IonCom is an ligand-specific method for small ligand (including metal and acid radical ions) binding site prediction. Starting from given sequences or structures of the query proteins, IonCom performs a composite binding-site prediction that combines ab initio training and template-based transferals. To enhance specificity and sensitivity, the server focuses on binding site prediction of thirteen most important small ligand molecules, including nine metal ions (Zn2+, Cu2+, Fe2+, Fe3+, Ca2+, Mg2+, Mn2+, Na+, K+) and four acid radical ions (CO32-, NO2-, SO42-, PO43-).


[View an example of output] [Download standalone IonCom program ] [Download dataset used to train/test IonCom ]

Input data

    Please copy and paste your data below (either structure in PDB format or sequence in FASTA format is acceptable)


    Or upload the stucture/sequence file:

Select ligand type

    I don't know the ligand types

    I know the ligand types

    • Zn2+
    • Cu2+
    • Fe2+
    • Fe3+
    • Ca2+
    • Mg2+
    • Mn2+
    • Na+
    • K+
    • CO32-
    • NO2-
    • SO42-
    • PO43-

Your email Address

Reference

  • Xiuzhen Hu, Qiwen Dong, Jianyi Yang, Yang Zhang. Recognizing metal and acid radical ion binding sites by integrating ab initio modeling with template-based transferals. Bioinformatics 32, no. 21 (2016): 3260-3269. [PDF]

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218