QUARK is a computer algorithm for ab initio protein
structure prediction and protein peptide folding, which aims to
construct the correct protein 3D model from amino acid
QUARK models are built from small fragments (1-20 residues long) by replica-exchange
Monte Carlo simulation under the guide of an atomic-level knowledge-based force field.
QUARK was ranked as the No 1 server in
Free-modeling (FM) in
Since no global template information is used in QUARK simulation,
the server is suitable for proteins that do not have homologous templates
in the PDB library.
Go to example
to view an example of QUARK output.
The server is only for non-commercial use.
Questions about the QUARK server can be posted at the
Service System Discussion Board