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I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

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SEGMER is a segmental threading algorithm designed to recoginzing substructure motifs from the Protein Data Bank (PDB) library. It first splits target sequences into segments which consists of 2-4 consecutive or non-consecutive secondary structure elements (alpha-helix, beta-strand). The sequence segments are then threaded through the PDB to identify conserved substructures. It often identifies better conserved structure motifs than the whole-chain threading methods, especially when there is no similar global fold existing in the PDB.

Our server will undergo maintenance from Oct. 7 to Oct. 21, 2019. You can submit jobs normally during this period, but the jobs will run after Oct. 21, 2019. We apologize for any inconvenience this may cause.

Cut and paste your sequence here (in FASTA format):

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ID: (optional, your given name of the protein)



  • The SEGMER program is downloadable at the download page.


    Reference:
    S. Wu, Y. Zhang. Recognizing Protein Substructure Similarity Using Segmental Threading. Structure, 2010 18: 858-867 (download the PDF file).
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