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I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE WDL-RF ATPbind DockRMSD DeepMSA FASPR

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13


TACOS (Template-based Assembly of Complex Structures) is designed to model the structures of protein-protein complexes based on a hierarchical approach of template identification and structural refinement. First, protein complex templates are identified by the multi-chain threading algorithms COTH and SPRING. The fragments excised from the multple threading alignments are then used to reassemble the complex structure by replica-exchange Monte Carlo simulations based on a composite knowledge-based force field. Final models are selected based on structure clustering by SPICKER and refined into full-atomic models by ModRefiner.

From May. 10 to Jul. 30, 2020 (CASP14 season), the TACOS server will be closed to external users. Jobs submitted during this period will be run after CASP. We apologize for any inconvenience this may cause.

The output of the TACOS server include (An example of the TACOS output):

Input your first sequence below ([30,1000] residues in FASTA format). Example input:

Or upload the sequence from your local computer:

Input your second sequence below ([30,1000] residues in FASTA format). Example input:

Or upload the sequence from your local computer:

Email: (mandatory, where results will be sent to)

ID: (optional, your given name of the protein)




Reference:

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