Running STRUM locally; is the systematic mode not available?

I've been thinking of setting up and running STRUM locally, as I need to obtain results for quite a few PDB structures.

However, in the README, the only information that is available is about the single point mutation mode. If I want to evaluate the effects of all possible mutations on a structure, do I have to manually specify all possible point mutations or is there a way for that to be done automatically by the program?

Thanks!