Hi all,
I would appreciate if someone can help me with my problem:
I have solved the structure of a new protein and want to model an ortholog on that one.
The first try was without any specific restriction which yielded in disulfide distances to far apart to be bonded. I tried to define restrictions (distance or connections) for the disulfide bonds in my target sequence according to my structure. Those restrictions were ignored and I got the same result as before.
I am aware that implementing the restriction might lead to a higher difference (RMSD) of the superimposed structures in some areas.
Using the alignment option only gives me error results even if I just tried the example file.
Thanks!