Hello,
I am working on a protein, the crystal structure of which was resolved. In the sequence, there is a 9-residue loop at the C termini. However, the structure of the loop is not resolved. (In PDB file, these residues are missing.) Thus, I would like to run de novo loop modeling to create the loop. The problem is the loop is an outage loop, only one side of the loop is constrained. Is it possible to use rosetta to make the loop? Could you please share with me a similar tutorial or course specific for this kind of loop? Thank you.
Best regards,