Hi,
Here are lines from a cscore file:
==================================================================
| Estimated accuracy of your models |
==================================================================
Estimated Clusters (N=20200)
--------------------- ------------------
Model# C-score TM-score RMSD (A) #decoys density
------ ------- ---------- -------- ------- -------
model1 -4.21 0.27+-0.08 14.1+-3.8 3333 0.021
model2 -4.31 2892 0.019
model3 -4.46 2244 0.016
model4 -4.75 1974 0.012
model5 -4.82 1625 0.011
The cscore values are less than -1.5 and the TM-score of the best model is 0.27
The first I-TASSER paper from 2008 mentions using a C-score cutoff > -1.5 for the models of correct topology and that TM-score > 0.5 corresponds approximately to two structures of the similar topology.
Given my best C-score is -4.21 and the corresponding TM-score is 0.27, what do these values signify about the best predicted structure ?
Thanks.